ITM2B

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ITM2B
Identifiers
Aliases ITM2B, ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, imBRI2, RDGCA, integral membrane protein 2B
External IDs MGI: 1309517 HomoloGene: 7388 GeneCards: ITM2B
Gene location (Human)
Chromosome 13 (human)
Chr. Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for ITM2B
Genomic location for ITM2B
Band No data available Start 48,233,158 bp[1]
End 48,270,357 bp[1]
RNA expression pattern
PBB GE ITM2B 217731 s at fs.png

PBB GE ITM2B 217732 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021999

NM_008410

RefSeq (protein)

NP_068839

NP_032436

Location (UCSC) Chr 13: 48.23 – 48.27 Mb Chr 13: 73.36 – 73.39 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Integral membrane protein 2B (ITM2B or BRI2) is a protein that in humans is encoded by the ITM2B gene.[5][6]

ITM2B or BRI2 is a gene located on chromosome 13. The gene is connected to familial Danish dementia and familial British dementia causing amyloid and pre-filbrillar effects similar to those seen in Alzheimer's.

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000136156 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022108 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Pittois K, Deleersnijder W, Merregaert J (Nov 1998). "cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B". Gene. 217 (1-2): 141–9. PMID 9795190. doi:10.1016/S0378-1119(98)00354-0. 
  6. ^ "Entrez Gene: ITM2B integral membrane protein 2B". 

Further reading[edit]