IgSF CAM

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Immunoglobulin-like adhesion molecules
Identifiers
SymbolIgSF CAM
Membranome221

IgSF CAMs (Immunoglobulin-like Cell Adhesion Molecules) are cell adhesion molecules that belong to Immunoglobulin superfamily.[1] It is regarded as the most diverse superfamily of CAMs. This family is characterized by their extracellular domains containing Ig-like domains. The Ig domains are then followed by Fibronectin type III domain repeats and IgSFs are anchored to the membrane by a GPI moiety. This family is involved in both homophilic or heterophilic binding and has the ability to bind integrins or different IgSF CAMs.

Examples[edit]

Junctional adhesion molecules
Identifiers
SymbolJAM
InterProIPR029871
Membranome212

Here is a list of some molecules of this family:

References[edit]

  1. ^ Abel Lajtha; Naren L. Banik; Naren Banik (2007). Handbook of neurochemistry and molecular neurobiology: Neural protein metabolism and function. シュプリンガー・ジャパン株式会社. pp. 41–. ISBN 978-0-387-30346-8. Retrieved 28 November 2010.