Immune response

From Wikipedia, the free encyclopedia
Jump to: navigation, search

Immune response is the immunological response originating from immune system activation by antigens, including immunity to pathogenic microorganisms and its products, as well as autoimmunity to self-antigens allergies, and graft ejections. In this process main cells involved are the T cells, B cells of lymphocytes, and macrophagea. These cells produce lymphokines that influence the other host cells activities. B cells mature to produce immunoglobulins or antibodies, that react with antigens. At same time, macrophages are processing the antigens into immunogenic units which stimulate B lymphocites to differentiation into antibody secreting plasma cells, stimulating the T cells to realise lymphokines.[1]

Complement is a group of normal serum proteins to aim immunity by becoming activated form as result of antigen-antibody interaction. The first contact with any antigen sensitize individual affected and promote the primary immune response. Next of the sensitized individuals with same antigen result in a more rapid and massive reaction, called the secondary immune response ("booster response" or the "anamnestic reaction"). It is most expressed in the level of circulating serum antibodies.[2][3]

The immune response can be transferred via serum antibodies introduction from sensitised to unsensitised individuals. It is highly specific for given antigen, and it is normally directed against foreign protein substances.[2]

References[edit]

  1. ^ King R. C., Stransfield W. D. (1998). Dictionary of genetics. New York, Oxford: Oxford University Press. ISBN 0-19-50944-1-7. 
  2. ^ a b Hadžiselimović R., Pojskić N. (2005). Uvod u humanu imunogenetiku / Introduction to Human Immunogenetics. Sarajevo: INGEB. ISBN 9958-9344-3-4. 
  3. ^ Lawrence E., Ed., ed. (1999). Henderson's Dictionary of Biological Terms. London: Longman. ISBN 0-582-22708-9. 

External links[edit]