Examples of common applications of immunoproteomics include:
- the isolation and mass spectrometric identification of MHC (major histocompatibility complex) binding peptides
- purification and identification of protein antigens binding specific antibodies (or other affinity reagents), and
- comparative immunoproteomics to identify proteins and pathways modulated by a specific infectious organism, disease or toxin.
An important aspect to proteomics in general is that mass spectrometry is the ultimate technique used for protein identification.
In addition to mass spectrometry, gel based, microarray based, and DNA based techniques, are also commonly used for identifying protein expression.
- Purcell, A. W.; J. J. Gorman (March 2004). "Immunoproteomics: Mass Spectrometry-based Methods to Study the Targets of the Immune Response". Molecular & Cellular Proteomics 3 (3): 193–208. doi:10.1074/mcp.R300013-MCP200. PMID 14718575. Retrieved 2006-11-21.
- Further reading on An Introduction to Protein Identification