The group was formed in 2008 by the guitarist Vadim "Vidick" Ozhog, the lead vocalist Elena Cataraga aka Lena Scissorhands, and the DJ Ivan Kristioglo aka DJ Kapa. They debuted on 3 August 2008 at a concert dedicated to Slayer. Later, on 8 August 2008, Infected Rain took part at a heavy metal festival in Crimea, named Red Alert. In late August, same year, they recorded their first demo CD composed of three songs ("With Me", "Parasite", and "No Idols"). Also, the group held a number of concerts in Chișinău and Ukraine.
Infected Rain took part at heavy metal festivals like Red Alert 2008, Metal Heads’ Mission 2009, RockHausen 2008/2009, Fuckin’FuckFest 3, Big Up! Urban Fest 2009 (where the band took the second place), and Forest Kap 2009/2010. In the summer of 2009 they released the "ЕР2009", composed of 6 songs (Judgmental Trap, Panika, No More, Escape, Go Away, and Homeless). The combination of female screaming, hard riffs and electronic samples brought to Infected Rain an individual style. In the winter of 2010 they shot their first video, for the song "Judgemental Trap". Then, the band held a number of concerts in Moldova and Romania. On 25 November 2011 the group released their first full-length album titled Asylum, and then the band went on a tour in Romania. In January 2012 was released the second video of the band, for the song "At The Bottom of The Bottle". In June 2012 Infected Rain has performed on the same stage with well-known bands like Mötley Crüe and Dimmu Borgir. In the summer of 2012 were released two songs with their videos: "Me Against You" (collaborating with Moldova Extreme Moto Cross), and "Stop Waiting". In the autumn of 2013 Infected Rain toured Romania, Ukraine, Russia and Bulgaria, as their first big tour. On 15 May 2014 they released a new full-length album titled Embrace Eternity. In the summer of 2014 the group took part at festivals like "FajtFest 2014"  (in the Czech Republic), Maraton Festival, ROUTE68 SUMMERFEST and Rockstadt Extreme Fest 2014 in Romania, where it performed along with groups like Obituary, Behemoth, Sodom, Katatonia, The Agonist, and others. Then the band went into a two-months tour across 12 European countries to support their new album. Next year the band released the songs Serendipity, Intoxicating, Mold, and Fool the Gravity. On 20 April 2017 was released a new full-length album titled "86", as American English slang for getting rid of something, ejecting someone, or refusing service, which is also appeared to be the birth year of the lead vocalist Lena Sсissorhands (1986). The album features 11 tracks. The three albums were recorded in a Moldovan studio named Must Music, and were produced by Valentin Voluța and Infected Rain. The lyrics for Infected Rain songs are written by Lena Sсissorhands, and they are in English. The music is composed mainly by the guitarist Vidick, with contributions from all other members. As a female frontman, Lena was noted for her tattoos and her strong vocals. She is coached by New York-based Melissa Cross. For her style, Lena was named by local media "the most eccentric vocalist of Moldova".
- Elena "Lena Scissorhands" Cataraga - vocals (2008–present)
- Vadim "Vidick" Ojog - guitars (2008–present)
- Vladimir Babici - bass (2008–present)
- Serghei Babici - guitars (2010–present)
- Eugen Voluta - drums (2012–present)
- Ivan Kristioglo (DJ Kapa) - disc jockey (2008-2010)
- Andrei "Mednyi" - guitars (2008-2010)
- Vadim Protsenko - drums (2008-2012)
- Asylum (2011)
- Embrace Eternity (2014)
- 86 (2017)
- Endorphin (2019)
- Ecdysis (2022)
- EP Judgemental Trap (2009)
- Demo 2008 (2008)
- "Stop Waiting" (2013)
- "Serendipity" (2016)
- "Intoxicating" (2016)
- "Mold" (2017)
- "Fool The Gravity" (2017)
- "Passerby" (2019)
- "The Earth Mantra" (2019)
- "Lure" (2019)
- "Storm" (2019)
- "Black Gold" (2019)
- "Postmortem Pt. 1" (2021)
- "Infected Rain sign to Napalm Records & release new track "Passerby"". The Rock Pit. 20 February 2019. Retrieved 20 February 2019.
- ""INFECTED RAIN" INTERVIEW by Trisha Lindley". mhf-mag.com. 7 February 2017. Retrieved 17 August 2017.
- "Infected Rain – Fresh Act December 2016". stalker-magazine.rocks. Retrieved 17 August 2017.
- "Ep 2009 par Infected Rain sur Apple Music". iTunes. Retrieved 2017-08-18.
- "Infected Rain now delivering their full-length debut album entitled "Asylum"". Archived from the original on 2017-08-16. Retrieved 2017-12-14.
- ROM, Bucharest — OST Fest 2012
- "The latest chart entry from Infected Rain "Me Against You"". Archived from the original on 2017-08-16. Retrieved 2017-12-14.
- Интервью с Infected Rain в честь выхода альбома Embrace Eternity
- Infected Rain at FajtFest 2014, Velké Meziříčí, ČR
- Maraton Festival 2014 în Pădurea Măgura
- ROUTE68 SUMMERFEST 2014 Gurasada Park, Romania
- Rockstadt Extreme Fest 2014 (Râșnov, Brașov, Romania)
- INFECTED RAIN – 86, bloodrockmedia.com
- About Infected Rain
- De vorbă cu Lena de la Infected Rain (in Romanian)
- Este cea mai excentrica solista de la noi! Cum si-a sarbatorit ziua de nastere, Elena din Infected Rain (in Romanian)