Inosine nucleosidase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
inosine nucleosidase
Identifiers
EC number3.2.2.2
CAS number9030-95-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an inosine nucleosidase (EC 3.2.2.2) is an enzyme that catalyzes the chemical reaction

inosine + H2O D-ribose + hypoxanthine

Thus, the two substrates of this enzyme are inosine and H2O, whereas its two products are D-ribose and hypoxanthine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is inosine ribohydrolase. Other names in common use include inosinase, and inosine-guanosine nucleosidase. This enzyme participates in purine metabolism.

References[edit]

  • Koch AL (November 1956). "Some enzymes of nucleoside metabolism of Escherichia coli". The Journal of Biological Chemistry. 223 (1): 535–49. PMID 13376622.
  • Tarr HL (March 1955). "Fish muscle riboside hydrolases". The Biochemical Journal. 59 (3): 386–91. PMC 1216255. PMID 14363106.