Inositol phosphate

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Phosphate group

Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:


Inositol triphosphate[edit]

Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans


Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression[1] and Steger[2] (both in Science Magazine).


  1. ^ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science. 299 (5603): 112–4. PMID 12434013. doi:10.1126/science.1078068. 
  2. ^ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science. 299 (5603): 114–6. PMC 1458531Freely accessible. PMID 12434012. doi:10.1126/science.1078062. 

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