Interleukin 10 receptor, beta subunit

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Interleukin 10 receptor, beta
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols IL10RB ; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2
External IDs OMIM123889 MGI109380 HomoloGene523 GeneCards: IL10RB Gene
RNA expression pattern
PBB GE IL10RB 209575 at tn.png
More reference expression data
Species Human Mouse
Entrez 3588 16155
Ensembl ENSG00000243646 ENSMUSG00000022969
UniProt Q08334 Q61190
RefSeq (mRNA) NM_000628 NM_008349
RefSeq (protein) NP_000619 NP_032375
Location (UCSC) Chr 21:
33.27 – 33.3 Mb
Chr 16:
91.41 – 91.43 Mb
PubMed search [1] [2]

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene.[1]

IL10RB has also recently been designated CDW210B (cluster of differentiation W210B).

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.[1]


Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.