Interleukin 10 receptor, beta subunit

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IL10RB
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, Interleukin 10 receptor, beta subunit, interleukin 10 receptor subunit beta
External IDs MGI: 109380 HomoloGene: 523 GeneCards: 3588
RNA expression pattern
PBB GE IL10RB 209575 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000628

NM_008349

RefSeq (protein)

NP_000619.3

n/a

Location (UCSC) Chr 21: 33.27 – 33.3 Mb Chr 16: 91.41 – 91.43 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene.[1]

IL10RB has also recently been designated CDW210B (cluster of differentiation W210B).

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.[1]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.