Interleukin 10 receptor, beta subunit

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IL10RB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, Interleukin 10 receptor, beta subunit, interleukin 10 receptor subunit beta
External IDsMGI: 109380 HomoloGene: 523 GeneCards: IL10RB
Gene location (Human)
Chromosome 21 (human)
Chr.Chromosome 21 (human)[1]
Chromosome 21 (human)
Genomic location for IL10RB
Genomic location for IL10RB
Band21q22.11Start33,266,358 bp[1]
End33,310,187 bp[1]
RNA expression pattern
PBB GE IL10RB 209575 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000628

NM_008349

RefSeq (protein)

NP_000619

n/a

Location (UCSC)Chr 21: 33.27 – 33.31 MbChr 16: 91.41 – 91.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene.[5]

IL10RB has also recently been designated CDW210B (cluster of differentiation W210B).

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.[5]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.