Interleukin 20 receptor, alpha subunit

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IL20RA
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIL20RA, CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA, Interleukin 20 receptor, alpha subunit, interleukin 20 receptor subunit alpha
External IDsOMIM: 605620 MGI: 3605069 HomoloGene: 8685 GeneCards: IL20RA
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for IL20RA
Genomic location for IL20RA
Band6q23.3Start136,999,971 bp[1]
End137,045,180 bp[1]
RNA expression pattern
PBB GE IL20RA 219115 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278722
NM_001278723
NM_001278724
NM_014432

NM_172786

RefSeq (protein)

NP_001265651
NP_001265652
NP_001265653
NP_055247

NP_766374

Location (UCSC)Chr 6: 137 – 137.05 MbChr 10: 19.71 – 19.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin 20 receptor, alpha subunit is a subunit for the interleukin-20 receptor. IL20RA is its human gene.[5]

The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000016402 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020007 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: IL20RA interleukin 20 receptor, alpha".

Further reading[edit]