Interventricular septum

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Interventricular septum
Section of the heart showing the ventricular septum.
Interior of dorsal half of heart of human embryo of about thirty-five days. (Labeled as 'septum inferius')
Artery anterior interventricular branch of left coronary artery and Posterior interventricular artery
Latin s. interventriculare cordis
MeSH A07.541.459
TA A12.1.00.013
FMA 7133
Anatomical terminology

The interventricular septum (IVS, or ventricular septum, or during development septum inferius), is the stout wall separating the lower chambers (the ventricles) of the heart from one another.

The ventricular septum is directed obliquely backward to the right, and curved with the convexity toward the right ventricle; its margins correspond with the anterior and posterior longitudinal sulci.


  • The greater portion of it is thick and muscular and constitutes the muscular interventricular septum.
  • Its upper and posterior part, which separates the aortic vestibule from the lower part of the right atrium and upper part of the right ventricle, is thin and fibrous, and is termed the membranous ventricular septum (septum membranaceum)..


  • The muscular part of the interventricular septum derives from the bulboventricular flange which is developed due to differential growth of primitive ventricle and bulbous cordis. Membranous part has a neural crest origin which connects the upper free margin of the bulboventricular flange and anterior and posterior endocardial cushions of atrio ventricular canal. It also gets attached to lower border of spiral septum or the aortico pulmonary septum.


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