Intranodal palisaded myofibroblastoma
|Intranodal palisaded myofibroblastoma|
|Micrograph of an intranodal palisaded myofibroblastoma. H&E stain.|
|Classification and external resources|
It afflicts predominantly males of middle age.
Signs and symptoms
The signs and symptoms are non-specific, i.e. it is not possible to diagnose an IPM from the symptoms and manner in which they present.
They have a rim of peripheral lymphoid tissue (remnant of a lymph node) and consist of spindle cells with nuclear palisading. Red blood cell extravasation is common and blood vessels surrounded by collagen with (fine) peripheral spokes (amianthoid fibers) are usually seen.
Simple surgical excision is considered curative. Rare recurrences have been reported.
- Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma". Arch Pathol Lab Med. 131 (2): 306–10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.
- Bigotti, G.; Coli, A.; Mottolese, M.; Di Filippo, F. (Sep 1991). "Selective location of palisaded myofibroblastoma with amianthoid fibres". J Clin Pathol. 44 (9): 761–4. doi:10.1136/jcp.44.9.761. PMC 496726. PMID 1918406.
- Creager, AJ.; Garwacki, CP. (May 1999). "Recurrent intranodal palisaded myofibroblastoma with metaplastic bone formation". Arch Pathol Lab Med. 123 (5): 433–6. doi:10.1043/0003-9985(1999)123<0433:RIPMWM>2.0.CO;2. PMID 10235504.