Isabella Brant (or Brandt; 1591– July 15, 1626 ) was a Flemishartists' model who was the first wife of painter Peter Paul Rubens. She was the daughter of Jan Brant, an important city official in Antwerp, and Clara de Moy. Brant married Rubens on 3 October 1609 in Saint Michael's Abbey, Antwerp. They had three children: Clara, Nikolaas and Albert. She was 34 years old when she died of the plague.