Isocodeine

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Isocodeine
Isocodeine structure.svg
Names
IUPAC name
(5α,6β)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol
Other names
6-Isocodeine; α-Isocodeine
Identifiers
509-64-8 YesY
ChemSpider 4481821
Jmol 3D model Interactive image
Properties
C18H21NO3
Molar mass 299.37 g·mol−1
Melting point 173 to 174 °C (343 to 345 °F; 446 to 447 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Isocodeine is an opioid research chemical related to codeine. It is an epimer of codeine that can be prepared from it by a Mitsunobu reaction.[1]

Dozens of derivatives and analogs of isocodeine and the related compound isomorphine have been produced.[2][full citation needed]

References[edit]

  1. ^ a b Simon, Csaba; Hosztafi, Sándor; Makleit, Sándor (1991). "Application of the Mitsunobu Reaction for the Preparation of Isomorphine and Isocodeine Derivatives". Synthetic Communications 21 (3): 407–412. doi:10.1080/00397919108016763. 
  2. ^ "Report of Committee on drug addiction, 1929-1941". National Research Council (US).