Isometheptene

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Isometheptene
Isometheptene.svg
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a601064
Routes of
administration
Oral
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ECHA InfoCard 100.007.236
Chemical and physical data
Formula C9H19N
Molar mass 141.254 g/mol
3D model (Jmol)
  (verify)

Isometheptene (usually as isometheptene mucate) is a sympathomimetic amine sometimes used in the treatment of migraines and tension headaches due to its vasoconstricting properties; that is, it causes constriction (narrowing) of blood vessels (arteries and veins). Along with paracetamol and dichloralphenazone, it is one of the constituents of Amidrine.

Chemistry[edit]

Isometheptene is a monounsaturated aliphatic secondary amine.

Mechanism of action[edit]

Isometheptene's vasoconstricting properties arise through activation of the sympathetic nervous system via epinephrine and norepinephrine. These compounds elicit smooth muscle activation leading to vasoconstriction by interacting with cell surface adrenergic receptors.[1]

See also[edit]

References[edit]