Isopropyl acetate

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Not to be confused with Isopropenyl acetate.
Isopropyl acetate
Skeletal formula of isopropyl acetate
Ball-and-stick model of the isopropyl acetate molecule
IUPAC name
1-Methylethyl acetate
Other names
Isopropyl acetate
1-methylethyl ester
2-propyl acetate
2-propyl ethanoate
methylethyl ethanoate
propan-2-yl ethanoate
108-21-4 YesY
Jmol-3D images Image
Molar mass 102.13 g·mol−1
Density 0.87 g/cm3
Melting point −73 °C (−99 °F; 200 K)
Boiling point 89 °C (192 °F; 362 K)
4.3 g/100 mL (27 °C)
Vapor pressure 42 mmHg (20°C)[1]
EU classification Highly Flammable F Irritant Xi
R-phrases R11, R36, R66, R67
S-phrases (S2), S16, S26, S29, S33
NFPA 704
Flammability code 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g., gasoline) Health code 1: Exposure would cause irritation but only minor residual injury. E.g., turpentine Reactivity (yellow): no hazard code Special hazards (white): no codeNFPA 704 four-colored diamond
Flash point 2 °C (36 °F; 275 K)
460 °C (860 °F; 733 K)
Explosive limits 1.8–7.8%
Lethal dose or concentration (LD, LC):
11,918 ppm (rat, 8 hr)[2]
US health exposure limits (NIOSH):
TWA 250 ppm (950 mg/m3)[1]
None established[1]
1800 ppm[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Isopropyl acetate is an ester, an organic compound which is the product of esterification of acetic acid and isopropanol. It is a clear, colorless liquid with a characteristic fruity odor.[3]

Isopropyl acetate is a solvent with a wide variety of manufacturing uses that is miscible with most other organic solvents, and moderately soluble in water. It is used as a solvent for cellulose, plastics, oil and fats. It is a component of some printing inks[3] and perfumes.

Isopropyl acetate decomposes slowly on contact with steel in the presence of air, producing acetic acid and isopropanol. It reacts violently with oxidizing materials and it attacks many plastics.[4]

Isopropyl acetate is quite flammable in both its liquid and vapor forms, and it may be harmful if swallowed or inhaled.[5]

The Occupational Safety and Health Administration has set a permissible exposure limit of 250 ppm (950 mg/m3) over an eight hour time-weighted average for workers handling isopropyl acetate.[6]


  1. ^ a b c d "NIOSH Pocket Guide to Chemical Hazards #0358". National Institute for Occupational Safety and Health (NIOSH). 
  2. ^ "Isopropyl acetate". Immediately Dangerous to Life and Health. National Institute for Occupational Safety and Health (NIOSH). 
  3. ^ a b "Isopropyl acetate". ChemViP. 
  4. ^ "ISOPROPYL ACETATE". International Chemical Safety Cards. 
  5. ^ "Iso-propyl Acetate". Material Safety Data Sheets. 
  6. ^ "NIOSH Pocket Guide to Chemical Hazards - Isopropyl acetate". Centers for Disease Control and Prevention.