Isopropyl nitrite

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Isopropyl nitrite
Isopropyl-nitrite-2D-skeletal.png
Isopropyl nitrite 3d structure.png
Clinical data
Synonyms Isopropyl alcohol nitrite; nitrous acid, isopropyl ester; 1-methylethyl nitrite; 2-propyl nitrite
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
ECHA InfoCard 100.007.982 Edit this at Wikidata
Chemical and physical data
Formula C3H7NO2
Molar mass 89.09
3D model (JSmol)
Density 0.8684 g/cm3
Boiling point 40 °C (104 °F)
  (verify)

The chemical compound isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a clear pale yellow oil.[1]

Applications[edit]

Isopropyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Isopropyl nitrite has largely replaced Isobutyl nitrite in poppers.

Safety[edit]

Isopropyl nitrite has been associated with eye maculopathy, visual impairment with central scotomata, bilateral foveal yellow spots, and inner segment/outer segment (IS/OS) junction disruption,[2] which may be reversible.[3]

The compound may also be potentially harmful to human body - inhaling isopropyl nitrite [and other alkyl nitrites] vapor could lead to headache and extremely low blood pressure as well as increased body temperature, even death.

References[edit]

  1. ^ Handbook of Chemistry and Physics, CRC Press, 85th edition
  2. ^ Davies, AJ; Kelly, SP; Naylor, SG; Bhatt, PR; Mathews, JP; Sahni, J; Haslett, R; McKibbin, M (2012). "Adverse ophthalmic reaction in poppers users: case series of 'poppers maculopathy'". Eye (Lond). 26: 1479–86. doi:10.1038/eye.2012.191. PMC 3496104Freely accessible. PMID 23079752. 
  3. ^ Inserm. "Des pertes visuelles chez les consommateurs de poppers". www.inserm.fr (in French). Retrieved 2017-01-23.