JWH-184

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JWH-184
JWH-184.png
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaC25H27N
Molar mass341.498 g·mol−1
3D model (JSmol)

JWH-184 is a synthetic cannabinoid receptor ligand from the naphthylmethylindole family. It is the carbonyl-reduced derivative of related compound JWH-122. The binding affinity of JWH-184 for the CB1 receptor is reported as Ki = 23 ± 6 nM.[1]

In the United States, all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-184 are Schedule I Controlled Substances.[2]

See also[edit]

References[edit]

  1. ^ Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, et al. (February 2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor". Bioorganic & Medicinal Chemistry. 11 (4): 539–49. doi:10.1016/s0968-0896(02)00451-0. PMID 12538019.
  2. ^ 21 U.S.C. § 812: Schedules of controlled substances