JWH-302 ( 1-pentyl-3-(3-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family, which acts as a cannabinoid agonist with moderate affinity at both the CB and 1 CB receptors. It is a 2 positional isomer of the more common drug JWH-250, though it is slightly less potent with a of 17 nM at CB K i 1, compared to 11 nM for JWH-250.  Because of their identical  molecular weight and similar fragmentation patterns, JWH-302 and JWH-250 can be very difficult to distinguish by GC-MS testing.
In the United States, CB
1 receptor agonists of the 3-phenylacetylindole class such as JWH-302 are Schedule I Controlled Substances.
References [ edit ]
Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, et al. (September 2005). "1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles". Bioorganic & Medicinal Chemistry Letters. 15 (18): 4110–3. doi: 10.1016/j.bmcl.2005.06.008. PMID 16005223.
Manera C, Tuccinardi T, Martinelli A (April 2008). "Indoles and related compounds as cannabinoid ligands". Mini Reviews in Medicinal Chemistry. 8 (4): 370–87. doi: 10.2174/138955708783955935. PMID 18473928.
'Herbal High' synthetic Cannabinoid composition, released by ESR July 2011
: 21 U.S.C. § 812 Schedules of controlled substances