On December 21, 2001, Cruz signed with the Detroit Tigers. Cruz played 35 games for the Tigers and was released on October 3, 2002. On December 27, 2002, Cruz signed with the Cincinnati Reds. He would spend the next three years in the Reds organization, including appearing in a career-high 110 games in 2005. Released by the Reds on April 14, 2006, Cruz signed a minor league contract with the New York Mets on May 30, 2006. Cruz played 55 games for the Mets Triple-A affiliate, the Norfolk Tides, the rest of the year and was granted free agency at the end of the season.
On December 13, 2010, the Arizona Diamondbacks hired Cruz to be the Hitting Coach of the Yakima Bears, the Diamondbacks Short Season Class A team. On November 22, 2011 Cruz was promoted to Hitting Coach of the Visalia Rawhide, the Diamondbacks Advanced Class A team.
^Riley, Jeff, Los Angeles Times, "Establishing Cruz Control Baseball: Rated one of the top outfielders in the nation, Channel Islands senior begins to meet his own lofty expectations." (Apr 24, 1991, Sports Section- Part C, Page 11); "Jacob Cruz, Sr. has been instrumental in his son's success He emigrated from Durango Mexico in 1964.."