James Learmonth Gowans

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Sir James Learmonth Gowans, CBE, FRS, FRCP (born 7 May 1924) is a British physician and immunologist.

Gowans was born in Sheffield, England. He graduated in medicine in 1947 from King's College Hospital in London, then in 1948 obtained a degree in physiology at Oxford, followed by a Ph.D. with Howard Florey at the Sir William Dunn School of Pathology at Oxford on lymphocytes. He then became professor of experimental pathology at Oxford. In 1977, he left his research career for ten years to be secretary of the Medical Research Council. He served as Secretary General of the Human Frontier Science Program in 1989.

He made significant discoveries about the role of lymphocytes in the immune response. In particular, he showed that some lymphocytes were not short-lived, as previously assumed, but moved from the blood into the lymphatic system and back. On the initiative of Peter Medawar he also undertook experiments on rats that showed that lymphocytes play an important role in transplant rejection.

In 1963 Gowans became a Fellow of the Royal Society. He was appointed a Commander of the Order of the British Empire in the 1971 New Year Honours for services to medical science and a Knight Bachelor in the 1982 New Year Honours.[1][2] In 1980 he was awarded the Wolf Prize in Medicine. He is a foreign member of the National Academy of Sciences and a SSI Honorary Member (1971),[3] and received several honorary doctorates. In 1968 he received the Gairdner Foundation International Award and in 1990 shared the first Medawar Prize with Jacques Miller. In 1974 he was awarded the Paul Ehrlich and Ludwig Darmstaedter Prize. He won the Royal Medal in 1976.[4]

In 1956 he married Moira Leatham, with whom he has a son and two daughters.


  • Brent, Leslie (1997). A history of Transplantation Immunology. Academic Press. pp. 116–117.
  1. ^ "No. 45262". The London Gazette (Supplement). 31 December 1970. p. 8.
  2. ^ "No. 48837". The London Gazette. 30 December 1981. p. 1.
  3. ^ http://www.scandinavianimmunology.nu/Honorary-Members.html
  4. ^ "Royal Medal". Retrieved 6 December 2008.