Jenifer Estess (1963–2003) was a Moline, Illinois-born theatre producer. She began her career as an actor after graduating from New York University with a B.A. in drama. She was a co-founder of the Naked Angels (theater company) theatre company in Manhattan; she was its producing director until 1993. She also helped found the Nantucket Film Festival and the New York Women's Film Festival.
Her memoir, Tales from the Bed: Living, Dying and Having It All, was published in 2004 and became a television movie starring Laura San Giacomo. She also started Project ALS, which raises funds for finding a cure for Lou Gehrig's disease, from which she suffered. She helped raise over $17,000,000 (USD) for the Project.
In 2000, she testified before Senator Arlen Specter’s sub-committee on Labor, Health, Human Services and Education. "My life and millions of others are in the hands of Congress. We are already seeing the incredible potential of stem cells to replace what is destroyed in ALS, but we need the federal government to mentor research along in the most responsible, humane way." Pointing out that, "non-profits like Project A.L.S. and private industry have started stem cell replacement on the right track," she urged Congress to "do the right thing and take us to the next level with this life-saving science."
- Jenifer Estess, 40; Fought Lou Gehrig's Disease, The New York Times, December 17, 2003