Jeremy Farrar

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Jeremy Farrar
OBE FRCP FRS FMedSci
Jeremy Farrar C0058569 Wellcome Images.jpg
Jeremy Farrar in 2009, portrait via wellcomeimges.org at the Wellcome Trust
Born Jeremy James Farrar
(1961-09-01) 1 September 1961 (age 56)[1]
Singapore
Education Churcher's College
Alma mater
Awards Ho Chi Minh Medal[3]
Scientific career
Fields
Institutions
Thesis Analysis of combinatorial immunoglobin libraries from a myasthenia gravis patient (1997)
Influences Cheryll Tickle[8][9]
Website

Jeremy James Farrar (born 1961)[1] OBE FRCP FRS FMedSci[3][10] is director of the Wellcome Trust, one of world’s largest and wealthiest research charities. He was previously a Professor of Tropical medicine at the University of Oxford.[1][7][11][12][13][14]

Education[edit]

Farrar was educated at Churcher's College[citation needed] and University College London Medical School,[8] from where he obtained a Bachelor of Science degree in Immunology in 1983 and a Bachelor of Medicine, Bachelor of Surgery degree in 1986.[2] Farrar completed his Doctor of Philosophy degree at the University of Oxford in 1998 on myasthenia gravis.[15]

Career and research[edit]

From 1996 until 2013, Farrar was Director of the Oxford University Clinical Research Unit in Vietnam.[5][16][17][18][19] Farrar was Professor of Tropical Medicine and Global Health at the University of Oxford from 2000 until 2013.[1] In 2013, Farrar was appointed Director of the Wellcome Trust.[1]

Farrar's research interests are in infectious diseases[8] such as Tuberculosis,[20] Dengue,[21][22][23][24] Typhoid fever, Malaria, and Influenza H5N1.[4][25][26][27]

He has supervised numerous PhD students including Jane Chun,[28] Abhilasha Karkey[29] and Vianney Tricou.[30]

Awards and honours[edit]

Farrar is a member of the Royal College of Physicians (MRCP) and a Fellow of the Academy of Medical Sciences (FMedSci). He was appointed Officer of the Most Excellent Order of the British Empire (OBE). His citation on election to the Academy of Medical Sciences reads:[31]

Jeremy Farrar is director of the Wellcome Trust-funded Oxford University Clinical Research Unit. Over the past ten years he has created a remarkable research institute in which his own research productivity has been phenomenal and an impressive training program has been developed. Under his direction the research programme has conducted seminal work on malaria, dengue, typhoid, tetanus, pyogenic and tuberculous meningitis and has become the leading centre for clinical research on avian influenza. These Pivotal clinical and virological studies have identified the dual importance of viral burden and the cytokine response to the lethal pathogenesis of avian influenza, and have described the rapid emergence of resistance to neuraminidase inhibitors. The unit has also conducted important research into Dengue shock syndrome, conducting the only large prospective randomised trials of fluid replacement and has provided an evidence-base for revision of the World Health Organisation classification. His commitment to fighting emerging infectious diseases at their source in developing countries is commendable and his contribution to capacity building in Vietnam and other countries is vital for the future of health care in these regions and serves as a model for others to follow.

Farrar was elected a Fellow of the Royal Society (FRS) in 2015.[10]

References[edit]

  1. ^ a b c d e Anon (2016). Farrar, Dr Jeremy James. ukwhoswho.com. Who's Who (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc.  closed access publication – behind paywall (subscription required)
  2. ^ a b "Jeremy Farrar". www.antimicrobe.org. 
  3. ^ a b "Jeremy Farrar - Epidemiologist". bbc.co.uk. BBC World Service. 
  4. ^ a b Woolhouse, Mark; Farrar, Jeremy (2014). "Policy: An intergovernmental panel on antimicrobial resistance". Nature. 509 (7502): 555–7. doi:10.1038/509555a. PMID 24877180. 
  5. ^ a b "Oxford University Clinical Research Unit". www.oucru.org. 
  6. ^ The Farrar Foundation, farrarfoundation.org
  7. ^ a b Farrar, J; Cressey, D (2014). "Straight talk with...Jeremy Farrar". Nature Medicine. 20 (2): 112. doi:10.1038/nm0214-112. PMID 24504397. 
  8. ^ a b c Jeremy Farrar Interviewed by Jim Al-Khalili on The Life Scientific, 2014-07-14
  9. ^ Tickle, C; Crawley, A; Farrar, J (1989). "Retinoic acid application to chick wing buds leads to a dose-dependent reorganization of the apical ectodermal ridge that is mediated by the mesenchyme". Development. 106 (4): 691–705. PMID 2562664. 
  10. ^ a b "Professor Jeremy Farrar OBE FMedSci FRS". London: Royal Society. Archived from the original on 2015-11-17. 
  11. ^ Van Noorden, Richard (2013). "Clinician to head Wellcome Trust: Jeremy Farrar to lead one of world's largest research charities". Nature. 497 (7447): 19. doi:10.1038/497019a. 
  12. ^ Maxmen, A. (2009). "Jeremy Farrar: When disaster strikes". Journal of Experimental Medicine. 206 (1): 4–5. doi:10.1084/jem.2061pi. PMC 2626674Freely accessible. PMID 19153250. 
  13. ^ Jeremy Farrar publications indexed by the Scopus bibliographic database, a service provided by Elsevier. (subscription required)
  14. ^ A very Wellcome appointment: Professor Jeremy Farrar, who takes over as director of the Wellcome Trust in October 2013, The Guaridan, 2013-04-25
  15. ^ Farrar, Jeremy (1997). Analysis of combinatorial immunoglobin libraries from a myasthenia gravis patient. solo.bodleian.ox.ac.uk (DPhil thesis). University of Oxford. EThOS uk.bl.ethos.339366. 
  16. ^ Watts, Geoff (2013). "Jeremy Farrar: Wellcome arrival from southeast Asia". The Lancet. 382 (9899): 1167. doi:10.1016/S0140-6736(13)62047-4. PMID 24095187. 
  17. ^ Jeremy Farrar on Connecting your research with society on YouTube
  18. ^ Exchanges at the Frontier: Jeremy Farrar on YouTube
  19. ^ Jeremy Farrar seeks innovative backgrounds to help fight infectious diseases, Wired UK on YouTube
  20. ^ Thwaites, G. E.; Nguyen, N. D.; Nguyen, N. H.; Hoang, H. T.; Do, D. T. T.; Nguyen, N. T. C.; Nguyen, N. Q.; Nguyen, N. T.; Nguyen, N. N.; Nguyen, N. T. N.; Nguyen, N. N.; Nguyen, N. H.; Vu, V. N.; Cao, C. H.; Tran, T. T. H.; Pham, P. P.; Nguyen, N. T.; Stepniewska, K.; White, N. J.; Tran, T. T.; Farrar, J. J. (2004). "Dexamethasone for the Treatment of Tuberculous Meningitis in Adolescents and Adults". New England Journal of Medicine. 351 (17): 1741–1751. doi:10.1056/NEJMoa040573. PMID 15496623. 
  21. ^ Tricou, V.; Vu, H. T.; Quynh, N. V.; Nguyen, C. V.; Tran, H. T.; Farrar, J.; Wills, B.; Simmons, C. P. (2010). "Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses". BMC Infectious Diseases. 10: 142. doi:10.1186/1471-2334-10-142. PMC 2895602Freely accessible. PMID 20509940. 
  22. ^ Guzman, M. G.; Halstead, S. B.; Artsob, H.; Buchy, P.; Farrar, J.; Gubler, D. J.; Hunsperger, E.; Kroeger, A.; Margolis, H. S.; Martínez, E.; Nathan, M. B.; Pelegrino, J. L.; Simmons, C.; Yoksan, S.; Peeling, R. W. (2010). "Dengue: A continuing global threat". Nature Reviews Microbiology. 8 (12): S7–16. doi:10.1038/nrmicro2460. PMC 4333201Freely accessible. PMID 21079655. 
  23. ^ Wills, B. A.; Dung, N. M.; Loan, H. T.; Tam, D. T. H.; Thuy, T. T. N.; Minh, L. T. T.; Diet, T. V.; Hao, N. T.; Chau, N. V.; Stepniewska, K.; White, N. J.; Farrar, J. J. (2005). "Comparison of Three Fluid Solutions for Resuscitation in Dengue Shock Syndrome". New England Journal of Medicine. 353 (9): 877–89. doi:10.1056/NEJMoa044057. PMID 16135832. 
  24. ^ Solomon, T.; Dung, N. M.; Vaughn, D. W.; Kneen, R.; Thao, L. T. T.; Raengsakulrach, B.; Loan, H. T.; Day, N. P.; Farrar, J.; Myint, K. S.; Warrell, M. J.; James, W. S.; Nisalak, A.; White, N. J. (2000). "Neurological manifestations of dengue infection". The Lancet. 355 (9209): 1053–1059. doi:10.1016/S0140-6736(00)02036-5. PMID 10744091. 
  25. ^ Farrar, J. (2012). "H5N1 surveillance: Shift expertise to where it matters". Nature. 483 (7391): 534–535. doi:10.1038/483534a. PMID 22460881. 
  26. ^ Hien, T. T.; Nguyen, N. T.; Nguyen, N. T.; Luong, L. T.; Pham, P. P.; Nguyen, N. V. V.; Pham, P. T.; Vo, V. C.; Le, L. T. Q.; Ngo, N. T.; Dao, D. B.; Le, L. P.; Nguyen, N. T.; Hoang, H. T.; Cao, C. V.; Le, L. T.; Nguyen, N. D.; Le, L. H.; Nguyen, N. T. K.; Le, L. H.; Le, L. V.; Christiane, C.; Tran, T. T.; Menno De, M.; Schultsz, C.; Cheng, P.; Lim, W.; Horby, P.; Farrar, J.; World Health Organization International Avian Influenza Investigative Team (2004). "Avian Influenza A (H5N1) in 10 Patients in Vietnam". New England Journal of Medicine. 350 (12): 1179–1188. doi:10.1056/NEJMoa040419. PMID 14985470. 
  27. ^ De Jong, M. D.; Simmons, C. P.; Thanh, T. T.; Hien, V. M.; Smith, G. J. D.; Chau, T. N. B.; Hoang, D. M.; Chau, N.; Khanh, T. H.; Dong, V. C.; Qui, P. T.; Cam, B.; Ha Do, D. Q.; Guan, Y.; Peiris, J. S. M.; Chinh, N. T.; Hien, T. T.; Farrar, J. (2006). "Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia". Nature Medicine. 12 (10): 1203–1207. doi:10.1038/nm1477. PMC 4333202Freely accessible. PMID 16964257. 
  28. ^ Chun, Jane M (2014). Livelihoods under stress: household assets and responses to environmental change in the Mekong Delta, Vietnam. ora.ox.ac.uk (DPhil thesis). University of Oxford. EThOS uk.bl.ethos.604488. 
  29. ^ Karkey, Abhilasha (2012). Evaluation of strain circulation and the epidemiology of enteric fever caused. ora.ox.ac.uk (DPhil thesis). University of Oxford. EThOS uk.bl.ethos.580993. Free to read
  30. ^ Tricou, Vianney M (2011). Dengue diagnostics and therapeutic interventions in Viet Nam. ora.ox.ac.uk (DPhil thesis). University of Oxford. 
  31. ^ "Dr Jeremy Farrar OBE FMedSci". London: Academy of Medical Sciences. Archived from the original on 2014-09-25. 
Cultural offices
Preceded by
Mark Walport
Director of the Wellcome Trust
2013 – date
Incumbent