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Litman graduated from Reed College, received an MFA from Southern Methodist University, and received a JD from Columbia Law School.  After law school, she served as a law clerk to Judge Betty Fletcher on the United States Court of Appeals for the Ninth Circuit.
She is John F. Nickoll Professor of Law at the University of Michigan Law School, after having been a law professor at Wayne State University Law School from 1990 to 2006 and University of Michigan Law from 1984 to 1990. She has also held a joint appointment as Professor of Information at the University of Michigan's School of Information, and has taught at schools including New York University and the University of Tokyo. Her original appointment to the Michigan Law faculty was only the fourth to that faculty of a woman.
Litman is the author of Digital Copyright: Protecting Intellectual Property on the Internet (2001), a classic text exploring the events leading to the passage of the Digital Millennium Copyright Act. The book's third edition was published in open-access form in 2017. She is also the co-author, with Jane Ginsburg and Mary Lou Kevlin, of the casebook Trademarks and Unfair Competition Law: Cases and Materials. Google Scholar lists Litman as the author of more than eighty articles, book chapters, or shorter works, published in the Yale Law Journal, the Stanford Law Review, the Columbia Law Review, the Texas Law Review, and elsewhere.
Litman has testified before Congress multiple times, most recently in 2020. According to digital libraries expert Karen Coyle, Litman’s 1994 testimony before the Working Group on Intellectual Property of the White House Information Infrastructure Task Force “leapt from the page like some minor miracle of truth and justice.”
Litman is a recipient of Public Knowledge’s IP3 award, awarded each year for significant contribution to “Intellectual Property, Information Policy, [or] Internet Protocol.” She is an elected member of the American Law Institute and an adviser to that body’s Restatement of the Law, Copyright. She serves on the advisory board of Cyberspace Law Abstracts, and is a member of the International Advisory Board of I/S: A Journal of Law and Policy for the Information Society. She has served as a trustee of the Copyright Society of the U.S.A., as a member of the advisory councils of both Public Knowledge and the Future of Music Coalition, and as chair of the Association of American Law Schools Section on Intellectual Property. She served on the Intellectual Property and Internet Committee of the ACLU. She served on the Program Committee of the 13th Annual Conference on Computers, Freedom & Privacy, and the organizing committee of the 25th Telecommunications Policy Research Conference. She was a member of the National Research Council's Committee on Partnerships in Weather and Climate Services.
- Digital Copyright: Protecting Intellectual Property on the Internet (2000)
- Trademark and Unfair Competition Law: Cases and Materials (2d ed. 1996 through 7th ed. 2022, with annual supplements), with Jane Ginsburg and Mary Lou Kevlin
- Rothman, Jennifer; Tushnet, Rebecca (26 February 2019). "Summary Judgments: The Implications of Trademark Forfeiture in U.S. v. Mongol Nation". Loyola Law School. Retrieved 2020-09-26.
- "Pitt Law School to Host 2008 Distinguished Lecture in Intellectual Property Law March 20 | University of Pittsburgh News". www.news.pitt.edu. Retrieved 2020-09-26.
- "Jessica Litman". University of Michigan. Retrieved 26 September 2020.
- Leiter, Brian. "Most Cited Law Professors by Specialty, 2000-2007". Leiter Law Reports. Retrieved 2021-02-16.
- "David L. Lange Lecture in Intellectual Property: Jessica Litman". David L. Lange Lecture. Duke Law. 2018-10-04.
- "Summary of Personnel Actions, [University of Michigan] Regents Agenda, September 2018" (PDF).>
- "First female professor at University of Michigan Law School teaches last class > Oakland County Legal News". legalnews.com. Retrieved 2020-09-26.
- Litman, Jessica (2017). Digital Copyright. doi:10.3998/mpub.9798641. ISBN 978-1-60785-418-0. S2CID 168807860.
- Rimmer, Matthew (2007-01-01). Digital Copyright and the Consumer Revolution: Hands Off My IPod. Edward Elgar Publishing. ISBN 978-1-84720-714-2.
- "Carolina Academic Press, Trademark and Unfair Competition Law: Cases and Materials, Seventh Edition". Retrieved 13 June 2022.
- "Google Scholar, User Profile for Jessica Litman". Retrieved 13 Jun 2022.
- Litman, Jessica (11 Feb 2020). "The Digital Millennium Copyright Act at 22: What Is It, Why Was It Enacted, and Where Are We Now?: Statement of Jessica Litman Before the United States Senate Committee on the Judiciary, subcommittee on Intellectual Property" (PDF).
- Coyle, Karen. "Book Review: Digital Copyright, published in published in Information Technology and Libraries, December 2001, pp. 220-222".
- Public Knowledge. "IP3 Awards Ceremony".
- "I/S: A Journal of Law and Policy for the Information Society, International Advisory Board". Retrieved 13 June 2022.
- "13th Annual Conference on Computers, Freedom & Privacy Conference, Program Committee and Advisory Board".
- Jones, Paul (17 Feb 1997). "Internet Policy: Call for Papers".
- National Research Council of the National Academy of Sciences (2003). FAIR WEATHER: Effective Partnership in Weather and Climate Services. Washington, D.C. p. iv. doi:10.17226/10610. ISBN 978-0-309-08746-9.
- "Working with Intellectual Property: Legal Histories of Innovation, Labor, and Creativity (Third Annual Conference of the Stanford Center for Law and History)".
- "Cardozo Arts & Entertainment Law Journal Spring 2021 Symposium, a Discussion and Celebration of the Diamond Anniversary of the Lanham Act".