John Hunter (surgeon)
13 February 1728|
Long Calderwood near East Kilbride, Scotland
|Died||16 October 1793
|Cause of death||Heart Attack|
|Education||St. Bartholomew's Hospital|
|Known for||Scientific method in medicine
Many discoveries in surgery & medicine
|Institutions||St George's Hospital|
|Research||Dentistry, gunshot wounds, venereal diseases, digestion, child development, foetal development, lymphatic system|
|Notable prizes||Copley Medal (1787)|
John Hunter FRS (13 February 1728 – 16 October 1793) was a Scottish surgeon, one of the most distinguished scientists and surgeons of his day. He was an early advocate of careful observation and scientific method in medicine. He was a teacher of, friend of, and collaborator with, Edward Jenner, the inventor of the smallpox vaccine. His wife, Anne Hunter (née Home), was a minor poet, some of whose poems were set to music by Joseph Haydn.
He learned anatomy by assisting his elder brother William with dissections in William's anatomy school in Central London, starting in 1748, and quickly became expert in anatomy. He spent some years as an Army surgeon, worked with the dentist James Spence conducting tooth transplants, and in 1764 set up his own anatomy school in London. He built up a collection of living animals whose skeletons and other organs he prepared as anatomical specimens, eventually amassing nearly 14,000 preparations demonstrating the anatomy of humans and other vertebrates.
Hunter became a Fellow of the Royal Society in 1767. The Hunterian Society of London was named in his honour, and the Hunterian Museum at the Royal College of Surgeons preserves his name and his collection of anatomical specimens.
Hunter was born at Calderwood, the youngest of ten children. The date of his birth is uncertain; Robert Chamber's "Book of Days" (1868) gives an alternative birth date of 14 July, and Hunter is recorded as always celebrating his birthday on this date rather than 13 July as shown in the parish register of the town of his birth. Family papers cite his birthday as being variously on 7 and 9 February. Three of Hunter's siblings (one of whom had also been named John) died of illness before he was born. An elder brother was William Hunter, the anatomist. As a youth, John showed little talent, and robbed his brother-in-law as a cabinet-maker.
Education and training
When nearly 21 he visited William in London, where his brother had become an admired teacher of anatomy. John started as his assistant in dissections (1748), and was soon running the practical classes on his own. It has recently been alleged that Hunter's brother William, and his brother's former tutor William Smellie, were responsible for the deaths of many women whose corpses were used for their studies on pregnancy. John is alleged to have been connected to these deaths, since at the time he was acting as William's assistant. However, persons who have studied life in Georgian London agree that the number of gravid women who died in London during the years of Hunter's and Smellie's work was not particularly high for that locality and time; the prevalence of pre-eclampsia, a common condition affecting ten percent of all pregnancies and one easily treated today, but for which there was no treatment in Hunter's time, would more than suffice to explain a mortality rate that seems suspiciously high to 21st-century readers. In The Anatomy of the Gravid Uterus Exhibited in Figures, published in 1774, Hunter provides case histories for at least four of the subjects illustrated.
Hunter heavily researched blood while bloodletting patients with various diseases. This helped him develop his theory that inflammation was a bodily response to disease, and was not itself pathological.
Hunter studied under William Cheselden at Chelsea Hospital and Percival Pott at St. Bartholomew's Hospital. Hunter also studied with Marie Marguerite Bihéron, a famous anatomist and wax modeler teaching in London; some of the illustrations in his text were likely hers. After qualifying he became Assistant Surgeon (house surgeon) at St George's Hospital (1756) and Surgeon (1768).
Hunter was commissioned as an Army surgeon in 1760 and was staff surgeon on expedition to the French island of Belle Île in 1761, then served in 1762 with the British Army. Contrary to prevailing medical opinion at the time, Hunter was against the practice of 'dilation' of gunshot wounds. This practice involved the surgeon deliberately expanding a wound with the aim of making the gunpowder easier to remove. Although sound in theory, in the unsanitary conditions of the time it increased the chance of infection, and Hunter's practice was not to perform dilation 'except when preparatory to something else' such as the removal of bone fragments.
Hunter left the Army in 1763, and spent at least five years working in partnership with James Spence, a well-known London dentist. Although not the first person to conduct tooth transplants between living people, he did advance the state of knowledge in this area by realising that the chances of a successful tooth transplant would be improved if the donor tooth was as fresh as possible and was matched for size with the recipient. These principles are still used in the transplanation of internal organs. Although donated teeth never properly bonded with the recipients' gums, one of Hunter's patients stated that he had three which lasted for six years, a remarkable period at the time.
Hunter set up his own anatomy school in London in 1764 and started in private surgical practice.
Earl's Court house
In 1765, Hunter bought a house near the Earl's Court district in London. The house had large grounds which were used to house a collection of animals including 'zebra, Asiatic buffaloes and mountain goats', as well as jackals. In the house itself, Hunter boiled down the skeletons of some of these animals as part of research on animal anatomy. A newspaper article reported that many animals there were 'supposed to be hostile to each other but . . . in this new paradise, the greatest friendship prevails', and this image may have been the inspiration for the Doctor Dolittle literary character.
Hunter was elected as Fellow of the Royal Society in 1767. At this time he was considered the leading authority on venereal diseases, and believed that gonorrhea and syphilis were caused by a single pathogen. Living in an age when physicians frequently experimented on themselves, he was the subject of an often-repeated legend claiming that he had inoculated himself with gonorrhea, using a needle that was unknowingly contaminated with syphilis. When he contracted both syphilis and gonorrhea, he claimed it proved his erroneous theory that they were the same underlying venereal disease. The experiment, reported in Hunter's A Treatise on the Venereal Diseases (part 6 section 2, 1786), does not indicate self-experimentation; this experiment was most likely performed on a third party. Hunter championed treatment of gonorrhea and syphilis with mercury and cauterization. Because of Hunter’s reputation, knowledge concerning the true nature of gonorrhea and syphilis was set back, and it was not until 51 years later that his theory was proved to be wrong, by the French physician Philippe Ricord.
In 1783 Hunter moved to a large house in Leicester Square, where today there stands a statue to him. The space allowed him to arrange his collection of nearly 14,000 preparations of over 500 species of plants and animals into a teaching museum. The same year, he acquired the skeleton of the 2.31 m (7' 7") Irish giant Charles Byrne against Byrne's clear deathbed wishes—he had asked to be buried at sea. Hunter bribed a member of the funeral party (possibly for £500) and filled the coffin with rocks at an overnight stop, then subsequently published a scientific description of the anatomy and skeleton. "He is now, after having being stolen on the way to his funeral," says Muinzer, "on display permanently as a sort of freak exhibit in the memorial museum to the person who screwed him over, effectively." The skeleton today, with much of Hunter's surviving collection, is in the Hunterian Museum at the Royal College of Surgeons in London.
In 1786 he was appointed deputy surgeon to the British Army and in March 1790 he was made Surgeon General by the then Prime Minister, William Pitt. While in this post he instituted a reform of the system for appointment and promotion of army surgeons based on experience and merit, rather than the patronage-based system that had been in place.
Hunter's death in 1793 followed a heart attack during an argument at St George's Hospital over the admission of students.
Hunter's character has been discussed by biographers:
His nature was kindly and generous, though outwardly rude and repelling.... Later in life, for some private or personal reason, he picked a quarrel with the brother who had formed him and made a man of him, basing the dissension upon a quibble about priority unworthy of so great an investigator. Yet three years later, he lived to mourn this brother's death in tears.
He was described by one of his assistants late in his life as a man 'warm and impatient, readily provoked, and when irritated, not easily soothed'.
In 1771 he married Anne Home, daughter of Robert Boyne Home and sister of Sir Everard Home. They had four children, two of whom died before the age of five. One of his infant children is buried in the churchyard in Kirkheaton, Northumberland, and the gravestone is Grade II listed. Their fourth child, Agnes, married General Sir James Campbell of Inverneill.
In 1799 the government purchased Hunter's collection of papers and specimens, which it presented to the Company of Surgeons.
Contributions to medicine
Hunter helped to improve understanding of human teeth, bone growth and remodelling; inflammation; gunshot wounds; venereal diseases; digestion; the functioning of the lacteals; child development; the separateness of maternal and foetal blood supplies; and the role of the lymphatic system.
Samuel Taylor Coleridge, a key figure in Romantic thought, science and medicine, saw in Hunter's work the seeds of Romantic medicine, namely as regards his principle of life, which he felt had come from the mind of genius.
- WHEN we stand before the bust of John Hunter, or as we enter the magnificent museum furnished by his labours, and pass slowly, with meditative observation through this august temple, which the genius of one great man has raised and dedicated to the wisdom and uniform working of the Creator, we perceive at every step the guidance, we had almost said, the inspiration, of those profound ideas concerning Life, which dawn upon us, indeed, through his written works, but which he has here presented to us in a more perfect language than that of words - the language of God himself, as uttered by Nature. That the true idea of Life existed in the mind of John Hunter I do not entertain the least doubt...
Hunter was the basis for the character "Jack Tearguts" in William Blake's unfinished satirical novel, An Island in the Moon. He is a principal character in Hilary Mantel's 1998 novel, The Giant, O'Brien.
It is possible that his Leicester Square house was the inspiration for the home of Dr Jekyll of the Robert Louis Stevenson novel The Strange Case of Dr Jekyll and Mr Hyde. Hunter's house had two entrances, one through which the living area for his family was accessible, and another, leading to a separate street, which provided access to his museum and dissecting rooms. This pattern echoes that of the house in the story, in which the respectable Dr Jekyll used one entrance to the house and Mr Hyde the other, less prominent, one.
He is also a prominent protagonist in the well-researched and beautifully written 2013 mystery novel The Dead Shall Not Rest by Tessa Harris.
A bust of John Hunter stands on a pedestal outside the main entrance to St George's Hospital in Tooting, South London, along with a lion and unicorn taken from the original Hyde Park Corner building, Lanesborough House. There is a bust of him in the South West corner of Lincoln's Inn Fields, and one in Leicester Square near where his central London home and anatomy school were situated.
The Hunterian Neurosurgical Laboratory of the Johns Hopkins Hospital is named after John Hunter. 
- Home, Everard, (1794) 'A short account of the life of the author' in A Treatise on the Blood, Inflammation and Gun-shot Wounds, by the late John Hunter.
- Dobson, Jessie, (1969) John Hunter, E&S Livingstone, Edinburgh and London.
- Kobler, John, (1960) The Reluctant Surgeon. A Biography of John Hunter, New York, Doubleday.
- Moore, Wendy (30 September 2010). The Knife Man. Transworld. ISBN 978-1-4090-4462-8.
- Paget, Stephen (1897). John Hunter, Man of Science and Surgeon. London: T. Fischer Unwin.
- Rogers, Garet (1958) Lancet, Bantam. Reissued as Brother Surgeons, Corgi, 1962; reprinted 1968.
- Moore, p. 43
- Brook C. 1945. Battling surgeon. Strickland, Glasgow. pp. 15–17
- Shelton, Don 2010. The Emperor's new clothes. J. Royal Society of Medicine, February.
- Shelton, Don. The real Mr Frankenstein: Sir Anthony Carlisle, medical murders, and the social genesis of Frankenstein. 
- Founders of British obstetrics 'were callous murderers', Denis Campbell, 7 February 2010, The Observer, accessed May 2010
- Inglis, Lucy. "Burking and Body-Snatching: The Deadly Side of Medicine in Georgian London". Archived 9 October 2011 at the Wayback Machine.
- Loudon, Irvine (1986). "Deaths in childbed from the eighteenth century to 1935". Medical History. 30 (1): 1–41. PMC . PMID 3511335. doi:10.1017/s0025727300045014.
- Bynum, W. F. (1994). Science and the Practice of Medicine in the Nineteenth Century. Cambridge University. pp. 14–15. ISBN 0-521-27205-X.
- June K. Burton (2007), Napoleon and the Woman Question: Discourses of the Other Sex in French Education, Medicine, and Medical Law, 1799-1815, Texas Tech University Press (2007), pp.81-82.
- Moore, p. 188, quoting Hunter's The Works, vol 3 p. 549
- Moore, p. 223-224
- Moore, p. 291-292, citing Laszlo Magyar's John Hunter and John Dolittle
- Goddard, Jonathan (2005). "The Knife Man: the Extraordinary Life and Times of John Hunter, Father of Modern Surgery". Journal of the Royal Society of Medicine. 98 (7): 335. PMC . doi:10.1258/jrsm.98.7.335.
- Conniff, Richard (2012). "How Species Save Our Lives". New York Times. Retrieved 9 March 2012.
- Gladstein, Jay (2005). "Hunter's chancre: did the surgeon give himself syphilis?". Clinical Infectious Diseases. 41 (1): 128; author reply 128–9. PMID 15937780. doi:10.1086/430834.
- Dr. Charles "Carl" Hoffman, Library of the History of Medical Sciences, Marshall University
- Moore, p. 268, citing Deborah Hayden's Pox: Genius, Madness and the Mysteries of Syphilis (2003) and Diane Beyer Perett's Ethics and Error: the dispute between Ricord and Auzias-Turenne over syphilization 1845-70 (1977)
- "The Saga Of The Irish Giant's Bones Dismays Medical Ethicists".
- Doctors: the biography of medicine by Sherwin B. Nuland.
- Moore, p477, citing Peterkin, Johnston & Drew, Commissioned Officers in the Medical Services of the British Army 1660-1960 (1968) vol 1, p. 33
- Moore, p478
- Garrison, Fielding H. 1913. An introduction to the history of medicine. Saunders, Philadelphia PA. p. 274
- Home, p. lxv cited in Moore, p. 346
- Wikisource:Hints towards the formation of a more comprehensive theory of life[page needed]
- Damon, S. Foster. A Blake Dictionary: The Ideas and Symbols of William Blake (Hanover: Brown University Press 1988; revised ed. 1988)[page needed]
- Moore, p. 430, citing The Sketch of 24 February 1897, which related that Stevenson 'is said to have chosen' Hunter's house as his inspiration.
- "John Hunter Clinic". Retrieved 19 January 2014.
- Moore, p. 546-7
- Sampath, Prakash; Long, Donlin M.; Brem, Henry (2000). "The Hunterian Neurosurgical Laboratory: the first 100 years of neurosurgical research". Neurosurgery. 46 (1): 184–94; discussion 194–5. PMID 10626949.
- "Review of John Hunter, Man of Science and Surgeon by Stephen Paget". The Athenæum (No. 3657): pp. 752–753. 27 November 1897.
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