Educated at King Edward VI School, Southampton and Keble College, Oxford, Muddiman studied for his DPhil under the supervision of G. B. Caird. and simultaneously served as Chaplain of New College, Oxford. Amongst his academic works he has produced a critically acclaimed examination of authorship in the Epistle to the Ephesians. Moreover, along with John Barton, he has co-edited the Oxford Bible Commentary, a particular favourite amongst undergraduate theologians. His most recent work is a study of the authenticity of the Pauline Epistles.