John Stein (physiologist)

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John Stein
John Frederick Stein
Scientific career
InstitutionsUniversity of Oxford
Doctoral studentsDaniel Wolpert

John Frederick Stein FRCPath FMedSci is a British physiologist. He is a fellow of Magdalen College, Oxford, and holds a professorship in physiology at the University of Oxford. He has research interests in the neurological basis of dyslexia.


A doctor of philosophy, Stein became a research biologist and neurologist and took up a teaching career. He is active in furthering the medical benefits of animal testing, speaking at pro-testing rallies and demonstrations, and has defended animal testing in high-profile television interviews.

He is the chair of the Dyslexia Research Trust[1] and is a proponent of the magnocellular theory of dyslexia. He has supervised many medical and physiology students at the University conducting laboratory work investigating the theory. He is a trustee of the Institute for Food, Brain and Behaviour[2] and Chair of the Institute's Science Advisory Council.[3]

Stein came into the public eye when Gordon Brown suggested a student had been discriminated against because of her state school education. This was despite the fact that she had comparable qualifications to the accepted applicants, who came from a broad range of backgrounds.

Stein is the brother of the chef Rick Stein, and the uncle of the DJ Judge Jules.

Stein was elected as a Fellow of the Academy of Medical Sciences in 2014.

Deep brain stimulation[edit]

Along with Tipu Aziz and Kevin Warwick, Stein is presently working on an intelligent Deep brain stimulation system for Parkinson's disease.

Dyslexia research[edit]

Alongside his former D.Phil. student, Joe Taylor, Stein has advocated a new theory of central noradrenergic deficiency in Dyslexia. Taylor and Stein have proposed that increasing noradrenergic output from the locus coeruleus via a subcortical irradiance detection pathway may prove effective in the treatment of the condition.[4]


  1. ^ "THE DYSLEXIA RESEARCH TRUST, registered charity no. 1052989". Charity Commission for England and Wales.
  2. ^ "INSTITUTE FOR FOOD, BRAIN AND BEHAVIOUR, registered charity no. 517817". Charity Commission for England and Wales.
  3. ^ "Science Advisory Council · About IFBB · Institute for Food, Brain and Behaviour". Archived from the original on 7 January 2016. Retrieved 18 October 2012.
  4. ^ Taylor, Visser and Stein. The efficacy of spectral filters in the upregulation of retinohypothalamic drive. Program No. 927.13. 2007. San Diego, CA: Society for Neuroscience, 2007.

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