Josann McGibbon's first major success as a screenwriter was the early Brad Pitt film, The Favor. Her biggest hits since then include Three Men and a Little Lady and Runaway Bride. In 2007, she co-wrote and produced the hit Debra Messing miniseries, The Starter Wife. The Starter Wife received 10 Emmy nominations in 2007, including for best screenwriting, and won one Emmy Award. It was also nominated for Golden Globe and Writers Guild awards, and was then produced as a series, also on USA Network. She and her long-time writing partner, Sara Parriott, wrote the Disney Channel movie, Descendants with a premiere in July, 2015, directed by Kenny Ortega.