Joseph R. Bertino

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Joseph R. Bertino
Born (1930-08-16) August 16, 1930 (age 88)
Alma mater
Spouse(s)Mary (d. 2011)
Scientific career

Joseph Rocco Bertino (born August 16, 1930) is a researcher in the cancer pharmacology program at Rutgers Cancer Institute of New Jersey and professor of medicine and pharmacology at the Robert Wood Johnson Medical School in New Jersey. His research is focused on the treatment of lymphoma.

Early life and education[edit]

Bertino was born in Port Chester, New York as the youngest son of Joseph and Mamie Bertino. His parents immigrated from Italy shortly before World War I.[1]

After graduating from medical school at SUNY Downstate College of Medicine in 1954, Bertino did a USPHS fellowship in hematology and oncology at the University of Washington School of Medicine. In 1958, he moved to Seattle to work with Clement A. Finch and Frank M. Huennekens.[1]

He has four children with his wife, Mary, who died in 2011.[1]


From 1973 to 1975, Bertino was the director of the Yale Cancer Center, until he was made an American Cancer Society Research Professor. He remained at Yale until 1987.[1] Following this, he was the chair of the Molecular Pharmacology and Therapeutics Program at Memorial Sloan-Kettering until 2002, when he moved to the Cancer Institute of New Jersey.[2][3]

Some of Bertino's notable scientific accomplishments are research into methotrexate and resistance to cancer treatments, including that use of methotrexate leads to an increase in dihydrofolate reductase. He is a founding editor of the Journal of Clinical Oncology.[2]



  1. ^ a b c d "Dr. Joseph Bertino's Breakthrough Work in Methotrexate Resistance Led to Understanding Why Cancer Drugs Work or Fail - The ASCO Post".
  2. ^ a b c "Joseph R. Bertino, MD".
  3. ^ Chabner, Bruce A. (1 October 2008). "Dr. Joseph R. Bertino: A Reflection". The Oncologist. pp. 1034–1035. doi:10.1634/theoncologist.2008-0211.
  4. ^ "Physician Profile | Rutgers Cancer Institute of New Jersey".