KCND1

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KCND1
Identifiers
Aliases KCND1, KV4.1, potassium voltage-gated channel subfamily D member 1
External IDs MGI: 96671 HomoloGene: 21035 GeneCards: 3750
RNA expression pattern
PBB GE KCND1 206842 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004979

NM_008423

RefSeq (protein)

NP_004970.3

NP_032449.1

Location (UCSC) Chr X: 48.96 – 48.97 Mb Chr X: 7.82 – 7.84 Mb
PubMed search [1] [2]
Wikidata
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Potassium voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as Kv4.1, is a human gene.[1]

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle.[1]

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Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.