KIF1B

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KIF1B
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KIF1B, CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1, kinesin family member 1B
External IDs MGI: 108426 HomoloGene: 99835 GeneCards: KIF1B
Genetically Related Diseases
multiple sclerosis[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_183416
NM_015074

NM_001290995
NM_008441
NM_207682

RefSeq (protein)

NP_055889.2
NP_904325.2

NP_001277924.1
NP_032467.2

Location (UCSC) Chr 1: 10.21 – 10.38 Mb Chr 4: 149.18 – 149.31 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIF1B is a protein that in humans is encoded by the KIF1B gene.[4][5][6]


Clinical significance[edit]

It is associated with Charcot–Marie–Tooth disease, type 2A1.[6]

Interactions[edit]

KIF1B has been shown to interact with GIPC1.[7]

References[edit]

  1. ^ "Diseases that are genetically associated with KIF1B view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T, Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N (Jun 2001). "Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta". Cell. 105 (5): 587–97. doi:10.1016/S0092-8674(01)00363-4. PMID 11389829. 
  5. ^ Nagai M, Ichimiya S, Ozaki T, Seki N, Mihara M, Furuta S, Ohira M, Tomioka N, Nomura N, Sakiyama S, Kubo O, Takakura K, Hori T, Nakagawara A (May 2000). "Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2". Int J Oncol. 16 (5): 907–16. doi:10.3892/ijo.16.5.907. PMID 10762626. 
  6. ^ a b "Entrez Gene: KIF1B kinesin family member 1B". 
  7. ^ Bunn, R C; Jensen M A; Reed B C (Apr 1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the Cytoskeleton". Mol. Biol. Cell. 10 (4): 819–32. doi:10.1091/mbc.10.4.819. ISSN 1059-1524. PMC 25204Freely accessible. PMID 10198040. 

Further reading[edit]

External links[edit]