KIF2C

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KIF2C
Protein KIF2C PDB 1v8j.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIF2C, CT139, KNSL6, MCAK, kinesin family member 2C
External IDsOMIM: 604538 MGI: 1921054 HomoloGene: 21355 GeneCards: KIF2C
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for KIF2C
Genomic location for KIF2C
Band1p34.1Start44,739,818 bp[1]
End44,767,767 bp[1]
RNA expression pattern
PBB GE KIF2C 211519 s at fs.png

PBB GE KIF2C 209408 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001297655
NM_001297656
NM_001297657
NM_006845

NM_001290662
NM_134471

RefSeq (protein)

NP_001284584
NP_001284585
NP_001284586
NP_006836

NP_001277591
NP_608301

Location (UCSC)Chr 1: 44.74 – 44.77 MbChr 4: 117.16 – 117.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.[5][6]

The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000142945 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028678 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kim IG, Jun DY, Sohn U, Kim YH (Feb 1998). "Cloning and expression of human mitotic centromere-associated kinesin gene". Biochim Biophys Acta. 1359 (3): 181–6. doi:10.1016/s0167-4889(97)00103-1. PMID 9434124.
  6. ^ a b "Entrez Gene: KIF2C kinesin family member 2C".

Further reading[edit]