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Kinesin family member 4A
Symbols KIF4A ; KIF4; KIF4G1; MRX100
External IDs OMIM300521 MGI108389 HomoloGene69022 ChEMBL: 6163 GeneCards: KIF4A Gene
RNA expression pattern
PBB GE KIF4A 218355 at tn.png
More reference expression data
Species Human Mouse
Entrez 24137 16571
Ensembl ENSG00000090889 ENSMUSG00000034311
UniProt O95239 P33174
RefSeq (mRNA) NM_012310 NM_008446
RefSeq (protein) NP_036442 NP_032472
Location (UCSC) Chr X:
70.29 – 70.42 Mb
Chr X:
100.63 – 100.73 Mb
PubMed search [1] [2]

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.[1][2]


Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division.[2]


KIF4A has been shown to interact with HMG20B[3] and DNMT3B.[4]


  1. ^ Ha MJ, Yoon J, Moon E, Lee YM, Kim HJ, Kim W (Jun 2000). "Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenetics and Cell Genetics 88 (1-2): 41–2. doi:10.1159/000015482. PMID 10773663. 
  2. ^ a b "Entrez Gene: KIF4A kinesin family member 4A". 
  3. ^ Lee YM, Kim W (Sep 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". The Biochemical Journal 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617. PMID 12809554. 
  4. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Research 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359. 

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