KIF4A

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KIF4A
Identifiers
Aliases KIF4A, KIF4, KIF4G1, MRX100, kinesin family member 4A
External IDs MGI: 108389 HomoloGene: 69022 GeneCards: KIF4A
Gene location (Human)
X chromosome (human)
Chr. X chromosome (human)[1]
X chromosome (human)
Genomic location for KIF4A
Genomic location for KIF4A
Band Xq13.1 Start 70,290,090 bp[1]
End 70,420,832 bp[1]
RNA expression pattern
PBB GE KIF4A 218355 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012310

NM_008446

RefSeq (protein)

NP_036442

NP_032472

Location (UCSC) Chr X: 70.29 – 70.42 Mb Chr X: 100.63 – 100.73 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.[5][6]

Function[edit]

Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division.[6]

Interactions[edit]

KIF4A has been shown to interact with HMG20B[7] and DNMT3B.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000090889 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034311 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Ha MJ, Yoon J, Moon E, Lee YM, Kim HJ, Kim W (Jun 2000). "Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenetics and Cell Genetics. 88 (1-2): 41–2. doi:10.1159/000015482. PMID 10773663. 
  6. ^ a b "Entrez Gene: KIF4A kinesin family member 4A". 
  7. ^ Lee YM, Kim W (Sep 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". The Biochemical Journal. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617Freely accessible. PMID 12809554. 
  8. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Research. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596Freely accessible. PMID 15148359. 

Further reading[edit]