KIFC1

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KIFC1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KIFC1, HSET, KNSL2, kinesin family member C1
External IDs MGI: 109596 HomoloGene: 83229 GeneCards: KIFC1
Gene location (Human)
Chromosome 6 (human)
Chr. Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for KIFC1
Genomic location for KIFC1
Band No data available Start 33,391,536 bp[1]
End 33,409,924 bp[1]
RNA expression pattern
PBB GE KIFC1 209680 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002263

NM_001195298

RefSeq (protein)

NP_002254

NP_001182227
NP_444403

Location (UCSC) Chr 6: 33.39 – 33.41 Mb Chr 6: 33.88 – 33.89 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[5][6]

Function[edit]

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References[edit]

  1. ^ a b c ENSG00000204197, ENSG00000237649, ENSG00000056678 GRCh38: Ensembl release 89: ENSG00000233450, ENSG00000204197, ENSG00000237649, ENSG00000056678 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079553 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. PMID 8276466. doi:10.1007/bf00241260. 
  6. ^ "Entrez Gene: KIFC1 kinesin family member C1". 

Further reading[edit]