KIFC1

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KIFC1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KIFC1, HSET, KNSL2, kinesin family member C1
External IDs MGI: 2137414 HomoloGene: 83229 GeneCards: 3833
RNA expression pattern
PBB GE KIFC1 209680 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002263

NM_016761
NM_053173

RefSeq (protein)

NP_002254.2

NP_001182227.1
NP_444403.2

Location (UCSC) Chr 6: 33.39 – 33.41 Mb Chr 17: 26.92 – 26.93 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[1][2]

Function[edit]

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References[edit]

  1. ^ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466. 
  2. ^ "Entrez Gene: KIFC1 kinesin family member C1". 

Further reading[edit]