KIFC1

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KIFC1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIFC1, HSET, KNSL2, kinesin family member C1
External IDsOMIM: 603763 MGI: 2137414 HomoloGene: 83229 GeneCards: KIFC1
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for KIFC1
Genomic location for KIFC1
Band6p21.32Start33,391,823 bp[1]
End33,409,896 bp[1]
RNA expression pattern
PBB GE KIFC1 209680 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002263

NM_016761
NM_053173

RefSeq (protein)

NP_002254

NP_444403
NP_001182227

Location (UCSC)Chr 6: 33.39 – 33.41 MbChr 17: 26.92 – 26.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[5][6]

Function[edit]

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References[edit]

  1. ^ a b c ENSG00000204197, ENSG00000237649, ENSG00000056678 GRCh38: Ensembl release 89: ENSG00000233450, ENSG00000204197, ENSG00000237649, ENSG00000056678 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024301 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466.
  6. ^ "Entrez Gene: KIFC1 kinesin family member C1".

Further reading[edit]

External links[edit]

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Kinesin-like protein KIFC1