Grew up in the Melpomene Projects, and then move to a house off the Parkway, also in Uptown. KLC dad was sazophonist, and KLC took up music as well. Nicknamed the Drum major even before he joined the band at Green Middle School, KLC became strongly attached to the candences of the marching band's snare-the sound would later influence his hip-hop beats. In high school, KLC got into breakdancing, one of his rivals being Michael "Mystikal Mike" Tyler. Tyler, aka Mystikal, would ultimately become a lifelong music associate.
After graduating high school, KLC and longtime friend Dartanian "MC Dart" Stovall started recording in a makeshift studio in the basement of KLC's home. Both had full-time, hourly jobs and one day decided to quit their jobs and devote their time to making music. They pooled their last paychecks and completed their first cassette. From these modest means, the teens established Parkway Pumpin' Records.
On Parkway Pumpin' there were no contracts, and artists including KLC himself often simultaneously worked at other labels. In 1994, KLC played keyboards and 39 Posse produced EXD's No Elevation for In the House Records. Mystikal (now minus the "Mike") recorded his debut album with Big Boy Records, where KLC also produced a track for veteran New Orleans rapper Sporty T. In 1995, Magnolia Slim aka Soulja Slim recorded The Dark Side EP (produced by KLC and featuring 6 Shot) at Hype Enough. Fiend followed Mystikal to Big Boy Records and recorded his debut album on that label.
From 1988 to present, KLC is credited (solo and with other Medicine Men team members) on close to 300 studio recordings covering over 100 studio albums. Lawson's RIAA accolades include eighteen gold albums, twelve platinum albums, four double-platinum albums, two triple-platinum albums, and one quadruple-platinum album as well as two gold singles, two platinum singles and one double-platinum single. Lawson has two Grammy nominations, both at the 45th Annual Grammy Awards for Best Rap Album (Word of Mouf by Ludacris and Tarantula by Mystikal) and two BMI Awards - one for the hit single Move Bitch (by Ludacris) and one for the associated album Word of Mouf.