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Kruppel-like factor 11
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols KLF11 ; FKLF; FKLF1; MODY7; TIEG2; Tieg3
External IDs OMIM603301 MGI2653368 HomoloGene2668 GeneCards: KLF11 Gene
RNA expression pattern
PBB GE KLF11 218486 at tn.png
More reference expression data
Species Human Mouse
Entrez 8462 194655
Ensembl ENSG00000172059 ENSMUSG00000020653
UniProt O14901 Q8K1S5
RefSeq (mRNA) NM_001177716 NM_178357
RefSeq (protein) NP_001171187 NP_848134
Location (UCSC) Chr 2:
10.04 – 10.05 Mb
Chr 12:
24.65 – 24.66 Mb
PubMed search [1] [2]

Krueppel-like factor 11 is a protein that in humans is encoded by the KLF11 gene.[1][2][3]


KLF11 has been shown to interact with SIN3A.[4][5]

See also[edit]


  1. ^ Cook T, Gebelein B, Mesa K, Mladek A, Urrutia R (Nov 1998). "Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth". J Biol Chem 273 (40): 25929–36. doi:10.1074/jbc.273.40.25929. PMID 9748269. 
  2. ^ Scohy S, Gabant P, Van Reeth T, Hertveldt V, Dreze PL, Van Vooren P, Riviere M, Szpirer J, Szpirer C (Jan 2001). "Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family". Genomics 70 (1): 93–101. doi:10.1006/geno.2000.6362. PMID 11087666. 
  3. ^ "Entrez Gene: KLF11 Kruppel-like factor 11". 
  4. ^ Zhang, J S; Moncrieffe M C; Kaczynski J; Ellenrieder V; Prendergast F G; Urrutia R (Aug 2001). "A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A". Mol. Cell. Biol. (United States) 21 (15): 5041–9. doi:10.1128/MCB.21.15.5041-5049.2001. ISSN 0270-7306. PMC 87230. PMID 11438660. 
  5. ^ Ellenrieder, Volker; Zhang Jin-San; Kaczynski Joanna; Urrutia Raul (May 2002). "Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor". EMBO J. (England) 21 (10): 2451–60. doi:10.1093/emboj/21.10.2451. ISSN 0261-4189. PMC 126002. PMID 12006497. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.