KLF5

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KLF5
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KLF5, BTEB2, CKLF, IKLF, Kruppel-like factor 5 (intestinal)
External IDs MGI: 1338056 HomoloGene: 37520 GeneCards: 688
RNA expression pattern
PBB GE KLF5 209211 at tn.png

PBB GE KLF5 209212 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001730
NM_001286818

NM_009769

RefSeq (protein)

NP_001273747.1
NP_001721.2

NP_033899.2

Location (UCSC) Chr 13: 73.05 – 73.08 Mb Chr 14: 99.3 – 99.31 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Krueppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene.[3][4]

Function[edit]

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.[4]

Interactions[edit]

KLF5 has been shown to interact with Protein SET.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Sogawa K, Imataka H, Yamasaki Y, Kusume H, Abe H, Fujii-Kuriyama Y (Apr 1993). "cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2". Nucleic Acids Research. 21 (7): 1527–32. doi:10.1093/nar/21.7.1527. PMC 309358free to read. PMID 8479902. 
  4. ^ a b "Entrez Gene: KLF5 Kruppel-like factor 5 (intestinal)". 
  5. ^ Miyamoto S, Suzuki T, Muto S, Aizawa K, Kimura A, Mizuno Y, Nagino T, Imai Y, Adachi N, Horikoshi M, Nagai R (Dec 2003). "Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain". Molecular and Cellular Biology. 23 (23): 8528–41. doi:10.1128/MCB.23.23.8528-8541.2003. PMC 262669free to read. PMID 14612398. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.