KRT32

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KRT32
Identifiers
AliasesKRT32, HA2, HKA2, KRTHA2, hHa2, keratin 32
External IDsMGI: 1309995 HomoloGene: 68246 GeneCards: KRT32
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT32
Genomic location for KRT32
Band17q21.2Start41,459,811 bp[1]
End41,467,429 bp[1]
RNA expression pattern
PBB GE KRT32 207146 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002278

NM_001159374
NM_010665

RefSeq (protein)

NP_002269

NP_001152846

Location (UCSC)Chr 17: 41.46 – 41.47 MbChr 11: 100.08 – 100.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.[5][6][7][8]

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108759 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046095 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Rogers MA, Nischt R, Korge B, Krieg T, Fink TM, Lichter P, Winter H, Schweizer J (Nov 1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes". Exp Cell Res. 220 (2): 357–62. doi:10.1006/excr.1995.1326. PMID 7556444.
  6. ^ Rogers MA, Winter H, Langbein L, Krieg T, Schweizer J (Dec 1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5". J Invest Dermatol. 107 (4): 633–8. doi:10.1111/1523-1747.ep12584243. PMID 8823373.
  7. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  8. ^ a b "Entrez Gene: KRT32 keratin 32".

Further reading[edit]