KRT78

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KRT78
Identifiers
Aliases KRT78, CK-78, K5B, K78, Kb40, keratin 78
External IDs MGI: 1917529 HomoloGene: 65261 GeneCards: 196374
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300814
NM_173352

NM_212487

RefSeq (protein)

NP_001287743.1
NP_775487.2

n/a

Location (UCSC) Chr 12: 52.84 – 52.85 Mb Chr 15: 101.95 – 101.95 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.[3][4]

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177free to read. PMID 16831889. 
  4. ^ a b "Entrez Gene: KRT78 keratin 78". 

Further reading[edit]