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Karl Broman

From Wikipedia, the free encyclopedia

Karl Broman is a professor at the University of Wisconsin–Madison (UWM) in the Biostatistics and Medical Informatics departments.[1] He has been employed at UWM since 2007 and previously was employed at Johns Hopkins University from 1999 - 2007.[1] Broman's original research focus was quantitative genetics,[2] although he has also become known for his work on reproducible research.[3] In 2016, Broman was named a Fellow of the American Statistical Association.


Study of Bile Acids[edit]

In 2019 Karl Broman and a group of researchers published a study which found genetic variants in mice that impacted the bile acid levels in their guts.[4]

Broman's other highly-cited papers include:

  • Broman, Karl W., et al. "Comprehensive human genetic maps: individual and sex-specific variation in recombination." The American Journal of Human Genetics 63.3 (1998): 861-869.
  • Broman, Karl W., et al. "R/qtl: QTL mapping in experimental crosses." Bioinformatics 19.7 (2003): 889-890.
  • Churchill, Gary A., et al. "The Collaborative Cross, a community resource for the genetic analysis of complex traits." Nature genetics 36.11 (2004): 1133.


Karl Broman created R (programming language) packages such as qtlcharts, QTL, and QTL2. These packages perform trait localization and visualizations of genetic data in high dimensions.[2]


  1. ^ a b ORCID. "Karl W Broman (0000-0002-4914-6671)". orcid.org. Retrieved 2020-04-01.
  2. ^ a b "Karl Broman". resources.rstudio.com. Retrieved 2020-04-01.
  3. ^ "Get With the Program". The Scientist Magazine®. Retrieved 2020-06-01.
  4. ^ "Study of bile acids links individual's genetics and microbial gut community: Gene identified in mice affects both size of a bacterial population and bile acid levels in blood". ScienceDaily. Retrieved 2020-04-01.