Karmacode is the fourth studio album by Italiangothic metal band Lacuna Coil, released on 31 March 2006 in several countries in Europe, 3 April in the UK and other European countries, 4 April in North America, and 5 April in several other European countries. 500,000 copies of Karmacode have officially been sold worldwide. In Italy the album sold over 20,000 copies, earning the album a Silver record. In the United States, the album sold around 200.000 copies.
Karmacode has a more prominent Middle-Eastern sound compared with Lacuna Coil's previous releases. The album is considered a blend of classical and modern rock, which is notably heavier and more metallic than previous releases.Popmatters comments that the album "doesn’t take any bold steps forward, but it still shows just how good Lacuna Coil are at what they do, presented in a high-gloss, primed-for-stardom package that is bound to go over huge".