Keratin 12

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KRT12
Identifiers
Aliases KRT12, K12, keratin 12
External IDs MGI: 96687 HomoloGene: 188 GeneCards: 3859
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000223

NM_010661

RefSeq (protein)

NP_000214.1

n/a

Location (UCSC) Chr 17: 40.86 – 40.87 Mb Chr 11: 99.42 – 99.42 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Keratin 12 is a protein that in humans is encoded by the KRT12 gene.[1][2]

Keratin 12 is keratin found expressed in corneal epithelia. Mutations in the gene encoding this protein lead to Meesmann corneal dystrophy.[1]

References[edit]

  1. ^ a b Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJ, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WH (June 1997). "Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy". Nat. Genet. 16 (2): 184–7. doi:10.1038/ng0697-184. PMID 9171831. 
  2. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 

Further reading[edit]