Keratin 34

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KRT34
Identifiers
Aliases KRT34, HA4, Ha-4, KRTHA4, hHa4, Keratin 34
External IDs MGI: 1309994 HomoloGene: 31083 GeneCards: KRT34
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT34
Genomic location for KRT34
Band 17q21.2 Start 41,377,650 bp[1]
End 41,382,403 bp[1]
RNA expression pattern
PBB GE KRT34 206969 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021013

NM_027563

RefSeq (protein)

NP_066293

NP_081839

Location (UCSC) Chr 17: 41.38 – 41.38 Mb Chr 17: 100.04 – 100.04 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene.[5][6][7][8]

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[8]

See also[edit]

References[edit]

  1. ^ a b c ENSG00000262045 GRCh38: Ensembl release 89: ENSG00000131737, ENSG00000262045 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043485 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Heid HW, Werner E, Franke WW (Feb 1987). "The complement of native alpha-keratin polypeptides of hair-forming cells: a subset of eight polypeptides that differ from epithelial cytokeratins". Differentiation. 32 (2): 101–19. PMID 2431943. doi:10.1111/j.1432-0436.1986.tb00562.x. 
  6. ^ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem. 273 (41): 26683–91. PMID 9756910. doi:10.1074/jbc.273.41.26683. 
  7. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. PMC 2064177Freely accessible. PMID 16831889. doi:10.1083/jcb.200603161. 
  8. ^ a b "Entrez Gene: KRT34 keratin 34". 

Further reading[edit]