Keratosis punctata of the palmar creases

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Keratosis punctata of the palmar creases (also known as "Hyperkeratosis penetrans," "Hyperkeratosis punctata," "Keratodermia punctata," "Keratosis punctata," "Keratotic pits of the palmar creases," "Lenticular atrophia of the palmar creases," and "Punctate keratosis of the palmar creases") is a common skin disorder that occurs most often in black patients, with skin lesions that are 1 to 5mm depressions filled with a comedo-like keratinous plug.[1]:212

Treatment with etretinate has been described.[2]

See also[edit]


  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ Just M, Ribera M, Bielsa I, Calatrava A, Ferrándiz C (September 1999). "Keratotsis punctata of the palmar creases: report of two cases associated with ichthyosis vulgaris". Br. J. Dermatol. 141 (3): 551–3. doi:10.1046/j.1365-2133.1999.03058.x. PMID 10583067.