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Ketotetrose-phosphate aldolase

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ketotetrose-phosphate aldolase
Identifiers
EC no.4.1.2.2
CAS no.9024-45-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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The enzyme ketotetrose-phosphate aldolase (EC 4.1.2.2) catalyzes the chemical reaction

erythrulose 1-phosphate glycerone phosphate + formaldehyde

Hence, this enzyme has one substrate, erythrulose 1-phosphate, and two products, dihydroxyacetone phosphate and formaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include phosphoketotetrose aldolase, erythrulose-1-phosphate synthetase, erythrose-1-phosphate synthase, and erythrulose-1-phosphate formaldehyde-lyase.

References

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  • CHARALAMPOUS FC, MUELLER GC (1953). "Synthesis of erythrulose phosphate by a soluble enzyme from rat liver". J. Biol. Chem. 201 (1): 161–73. PMID 13044785.