Kharoti (Pashto: خروټی) is a Pashtun tribe of Ghilji origin based in parts of Afghanistan and Pakistan. Many of the Kharoti have business in gulf countries and Pakistan. They have an estimated population of about 5.5 million, making it one of, if not the largest tribes in Afghanistan, Pakistan with significant territory throughout eastern and south-eastern Afghanistan. There are major Kharoti populations in the Paktika districts of Urgun, Barmal, Sar Hawza, Zarghun Shahr, Omna, Surobi and Gomal. The Kharoti also have a strong presence in balochistan, dera ismail khan and karachi and Ghazni, Zabul, Paktia, Khost, Logar, Wardak, Kabul, Nangarhar and Helmand.
As Pashtuns of the Ghilji confederacy, the heyday of the Kharotis were during the peak of their Khans of the Nasher-Nashir family. With the rise of Ghilji's rival confederacy, the Durrani in the 18th century, the Kharoti lost their leading role in Afghan politics but remained strong in the Afghan rural regions. However, they often view themselves as the 'true Pashtuns' and being Ghilji as the rightful leaders of kpk (Pakistan) and(Afghanistan)
- Sher Khan Nasher Loe Khan (Grand Khan) founder of Spinzar Cotton Company and founding father of Kunduz
- Gholam Serwar Nasher Khan (1922–1984), president of Spinzar Cotton Company
- Gholam Nabi Nasher Khan (1926–2010), parliamentarian
- Hafizullah Amin, politician and president of Afghanistan
- Gulbuddin Hekmatyar, warlord and former minister
- Farhad Darya Nasher Khan (born 1962), singer and composer.
- Mirwais ashraf, Afghanistan National Cricket Team Player.
- Matiullah Mati Kharoti, Politician and Afghanistan's Director of Education.
- Paktika Personalities: An Examination of the Tribes and the Significant People of a Traditional Pashtun Province - Timothy S. Timmons and Rashid Hassanpoor (2007)
- "Paktya Province". The Program for Culture & Conflict Studies. Retrieved 19 March 2015.