Klebsiella oxytoca

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Klebsiella oxytoca
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacteriales
Family: Enterobacteriaceae
Genus: Klebsiella
Species: K. oxytoca
Binomial name
Klebsiella oxytoca
(Flügge 1886)
Lautrop 1956

Klebsiella oxytoca is a Gram-negative, rod-shaped bacterium that is closely related to K. pneumoniae, from which it is distinguished by being indole-positive; it also has slightly different growth characteristics in that it is able to grow on melezitose, but not 3-hydroxybutyrate.

K. oxytoca is characterized by negative methyl red, positive VP, positive citrate, urea and TSI gas production, is AA, and negative for TSI sulfide, DNAse, growth on sulfide-indole motility medium and the phenylalanine deaminase test.

It is a diazotroph, able to colonise plant hosts and fix atmospheric nitrogen into a form which the plant can use. Association of K. oxytoca with the barley rhizosphere during an entire vegetative period has been demonstrated. The bacteria adhere strongly to root hairs, and less strongly to the surface of the zone of elongation and root cap mucilage.[1]

Industrial uses[edit]

K. oxytoca has shown promise in industrial ethanol fuel production,[2] and is referenced as being used to produce hydrogen in patents filed by Nanologix, Inc.

Clinical significance[edit]

It can cause colitis and sepsis.[3]


  1. ^ Brisse S, Grimont F & Grimont P AD (2006). Prokaryotes. New York, NY: Springer New York. pp. 159–196. 
  2. ^ Dien B, Cotta M, Jeffries T (2003). "Bacteria engineered for fuel ethanol production: current status". Appl Microbiol Biotechnol. 63 (3): 258–66. PMID 13680206. doi:10.1007/s00253-003-1444-y. 
  3. ^ Högenauer C, Langner C, Beubler E, et al. (December 2006). "Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis". N. Engl. J. Med. 355 (23): 2418–26. PMID 17151365. doi:10.1056/NEJMoa054765. 

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