The Kolinbiné River is a river in West Africa. It arises in southern Mauritania and flows south, forming part of the international boundary between Mauritania and Mali. In Mali, it joins the Sénégal River 5 km upstream from the town of Kayes.
The river flows through a number of shallow depressions that fill with water during the short rainy season (July to September). The largest of these is Lake Magui that extends for nearly 30 km in a north-south direction. The lake lies 55 km northeast of Kayes at. The river also fills Lake Doro which lies 34 km east-northeast of Kayes, just north of the RN1 highway at .
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