Slit lamp photograph showing Krukenberg's Spindle as pigment cell deposits on the cornea
|Classification and external resources|
Krukenberg's spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells which are deposited as a result of the currents of the aqueous humor. The sign was described in 1899 by Friedrich Ernst Krukenberg (1871-1946), who was a German pathologist specialising in Ophthalmology.
- Painful red eye with photophobia associated with inflammation
- Corneal deposits also known as Cornea verticillata, caused by chronic amiodarone use for cardiac arrhythmias.
- Non-transparent collagen deposits appearing following loss of corneal endothelial cells
- Krukenberg F. (1899) Beiderseitige angeborene Melanose der Hornhaut. Klin Mbl Augenheilkd 37:254-258.
- Chew, E; Ghosh, M; McCulloch, C (June 1982). "Amiodarone-induced cornea verticillata.". Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. 17 (3): 96–9. PMID 7116220.
- Akimune C, Watanabe H, Maeda N, et al. (January 2000). "Corneal guttata associated with the corneal dystrophy resulting from a betaig-h3 R124H mutation". 84 (1): 67–71. PMC . PMID 10611102.