Kurloff cell

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Kurloff cell
Kurloff cell and a lymphocyte in a Guinea pig

Kurloff cells (also known as Foà-Kurloff cells[1]) are found in the blood and organs of guinea pigs that contain large secretory granules but are of unknown function (also known as Kurloff bodies). They are also found in the capybara. Scientists speculate that these cells along with asparaginase may be what gives the guinea pig cancer resistant properties (Sharon Vanderlip, DVM). The Kurloff cell has NK cytotoxic activity in vitro.[2][3]

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References[edit]

  1. ^ Ledingham JCG (1940). "Sex hormones and the Foà‐Kurloff cell". The Journal of Pathology and Bacteriology. 50 (2): 201–219. doi:10.1002/path.1700500202. 
  2. ^ James G. Fox; et al. (2002). Laboratory Animal Medicine (2nd ed.). Academic Press. p. 206. 
  3. ^ Debout C; Quillec M; Izard J (1984). "Natural killer activity of Kurloff cells: a direct demonstration on purified Kurloff cell suspensions". Cellular Immunology. 87 (2): 674–677. doi:10.1016/0008-8749(84)90034-0.