|Subdivisions||1 city, 6 municipalities|
|• Total||6,072 km2 (2,344 sq mi)|
|• Density||70/km2 (180/sq mi)|
|ISO 3166 code||GE-KK|
Kvemo Kartli is a region located in the Southeastern part of Georgia. It is surrounded by Tbilisi, Shida Kartli, and Mtskheta-Mtianeti on the north; Samtskhe-Javakheti on the west; Kakheti on the east; and the countries of Armenia and Azerbaijan on the south.
The region is one of the most economically developed in Georgia. After Tbilisi, the region is ranked second in industrial production. The area of the region is of 6528 km squares, which accounts for 10% of the Georgian territory; and is the fourth most big region. The region is the third most populated region in Georgia with a population of 497.000. The administrative center is Rustavi. There are 353 populated areas, including :
- 7 cities : Rustavi, Bolnisi, Gardabani, Dmanisi, Tetritsqaro, Marneuli and Tsalka
- 8 "daba" : Didi Lilo, Kojori, Kazreti, Manglisi, Tamarisi, Shaumiani, Bediani and Trialeti
- 338 villages
The population is mixed between Georgians 217305 (51.25%), Azerbaijanis 177032 (41.75%), Armenians 21500 (5.07%), Russians 2113 (0.49%), Pontic and Caucasus Greeks 2631 (0.62%) and others. The current governor is Paata Khizanashvili 
The ethnic Georgians live mostly in northern part of the region and comprise for the majority in the municipalities of Tetritsqaro, Gardabani Municipality, Tsalka and in Rustavi. The Azerbaijanis live in the southern part and comprise for the majority in the municipalities of Marneuli, Dmanisi and Bolnisi. The ethnic Armenians and Greeks mostly live in the Tsalka Municipality.
The population estimate in 2012 was 511,300, but the 2014 census shows it now reduced to about 424,000.
According to a study, 57,8% of the population identifies as Orthodox Christians, mostly Georgians, Russians and Greeks; 38,9 % are Shia Muslims, mostly Azerbaijanis; 2,8% are Armenian Christians and 0,5% are irreligious.
Kvemo Kartli is divided into 6 municipalities and 1 special status city, Rustavi :
- Bolnisi Municipality
- Gardabani Municipality
- Dmanisi Municipality
- Marneuli Municipality
- Tetritsqaro Municipality
- Tsalka Municipality
Owing to its location, the region has great transport links. There passes the railway and the motorways which link Georgia with its neighbours Armenia and Azerbaijan. The main industries are located in Rustavi and Marneuli. The industrial production of Kvemo Kartlo comprises 20% of the global Georgian production.